{"product_id":"dfh-berb-evail","title":"Designs for Health Berb-Evail","description":"\u003cp\u003e\u003cstrong\u003eDesigns for Health's Berb-Evail 60 capsules\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eMaintains healthy blood glucose and liver health\u003c\/p\u003e\n\u003cul class=\"bullet-list-content\"\u003e\n\u003cli\u003eProvides equivalent to 2.5g of dry berberis root per capsule\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003eStandardised to 250mg of Berberine per capsule\u003c\/li\u003e\n\u003cli\u003eEvail™ Technology delivery system for optimal absorption\u003c\/li\u003e\n\u003cli\u003eCardiovascular system health support\u003c\/li\u003e\n\u003cli\u003eMaintains healthy cholesterol and levels\u003c\/li\u003e\n\u003cli\u003eSupports healthy blood glucose levels\u003c\/li\u003e\n\u003cli\u003eAssists liver health\u003c\/li\u003e\n\u003cli\u003eAntioxidant support\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eServings per bottle: 60 soft capsules\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eDirections for use\u003c\/strong\u003e\u003cbr\u003eAdults: Take 2 capsules 3 times per day, or as professionally prescribed. \u003cbr\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eAllergen Information\u003c\/strong\u003e\u003cbr\u003eNo added: Gluten, Dairy, Lactose, Seeds or Nuts\u003c\/p\u003e\n\u003cp\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"text-decoration: underline; color: #000000;\"\u003e\u003cstrong\u003eProduct Education:\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003eBerberis aristata is a deciduous evergreen herb indigenous to subtropical climates including India, Nepal, Asia and South America that has been used medicinally since ancient times in Ayurvedic and Chinese paradigms. Berberis aristata is considered to be one of the most medicinally significant herbs within the Berberis genus due to its broad therapeutic actions, mainly attributed to the alkaloid berberine. Within these traditional paradigms, such medicinal uses included as an antioxidant, blood sugar balancer, lipometabolic, anti-inflammatory, hepatoprotective and digestive supporting agent.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eEvail™ Technology\u003c\/strong\u003e\u003cbr\u003eHarnessing berberine’s therapeutic potential requires optimal absorption and delivery of a component that usually has suboptimal oral bioavailability due to enterocyte P-glycoproteins limiting its intestinal absorption. The Designs for Health Evail™ Process is specifically formulated to enhanced absorption of difficult to absorb ingredients such as berberine. It is manufactured using the Designs for Health Evail™ technology, which is an all-natural formulation that improves absorption and delivery. This process uses a proprietary blend of sustainable MCT oils, non-soy derived sunflower lecithin, and gamma tocopherol vitamin E, without the use of potentially harmful surfactants.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eAntioxidant\u003c\/strong\u003e\u003cbr\u003eBerberine has demonstrated antioxidant properties. Specifically, berberine reduces oxidative stress via significant superoxide and hydroxyl scavenging activity and by enhancing endogenous antioxidant system levels and activity (i.e. glutathione, glutathione peroxidase, superoxide dismutase).\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eCardiovascular system health\u003c\/strong\u003e\u003cbr\u003eExperimental and clinical evidence has shown berberine to have cardio-supportive and lipid metabolic-modulating effects. It helps to maintain cardiovascular system health, healthy blood lipids and cholesterol levels (particularly total cholesterol, low- and high-density lipoproteins and triglycerides) via several mechanisms. These include upregulating hepatic low-density lipoprotein receptor (LDLR) mRNA expression and protein levels, inhibiting lipogenesis and cellular lipid accumulation.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eBlood glucose levels\u003c\/strong\u003e\u003cbr\u003eThe long traditional use of berberine for maintaining blood sugar in Ayurvedic and Chinese paradigms has been validated by current clinical evidence demonstrating its effects on glucose metabolism involving insulin-mimetic and- independent mechanisms. In particular, along with its antioxidant mechanisms, berberine helps support healthy blood glucose levels by stimulating glycolysis, activating glucokinase and glucose-6-phosphate dehydrogenase activity and the AMP-activated protein-kinase pathway, modulating insulin receptor activity, promoting insulin sensitization and muscle glucose uptake and beneficially modulating the gastrointestinal microbiome.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eAntiviral activity of berberine\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003ca rel=\"noopener\" href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC7320912\" target=\"_blank\"\u003eStudies\u003c\/a\u003e have show it has the ability to inhibit infection of various viruses including influenza virus, HSV, HCMV and CHIKV, and to reduce virus production. Many viruses can target the MAPK pathway to manipulate cellular functions and control viral replication, leading to host cell death. These pathways are also involved in inhibitory effect of berberine. In addition, it can inhibit inflammatory responses triggered by viruses.\u003c\/p\u003e\n\u003cp\u003e\u003ca rel=\"noopener\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/32594322\/\" target=\"_blank\"\u003eStudies\u003c\/a\u003e have found it reduces virus replication and targets specific interactions between the virus and its host. It intercalates into DNA and inhibits DNA synthesis and reverse transcriptase activity. It inhibits replication of herpes simplex virus (HSV), human cytomegalovirus (HCMV), human papillomavirus (HPV), and human immunodeficiency virus (HIV). This isoquinoline alkaloid has the ability to regulate the MEK-ERK, AMPK\/mTOR, and NF-κB signaling pathways, which are necessary for viral replication. Furthermore, it has been reported that berberine supports the host immune response, thus leading to viral clearance. \u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003eCombined with Designs for Health Evail Technology for improved absorption and delivery.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003ePrescribing Information (considerations, contraindications)\u003cbr\u003e\u003c\/strong\u003e- Contraindicated for use during pregnancy and lactating women.\u003cbr\u003e- May enhance effects of medications that interfere with bilirubin protein binding.\u003cbr\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003eOnce supplements leave our store they cannot be returned or refunded. Please choose carefully.\u003c\/p\u003e","brand":"Designs for Health","offers":[{"title":"Default Title","offer_id":52009691283761,"sku":null,"price":46.95,"currency_code":"AUD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0951\/1338\/0145\/files\/DFH_Berb-Evail_800px_APR22.png?v=1762308778","url":"https:\/\/shop.healthhunter.au\/products\/dfh-berb-evail","provider":"Health Hunter","version":"1.0","type":"link"}